Session 9 – Standards and Tools for Lipid Data Processing & Analysis


Lipid molecular timeline profiling reveals diurnal crosstalk between the liver and circulation

Christer’s research interests are focused on development of lipidomics technology and combining this with other -omics technologies for systems biology studies of the regulation of lipid metabolism in cells and animals.

Christer carried out his PhD work at the Max Planck Institute of Molecular Cell Biology and Genetics in the labs of Andrej Shevchenko and Kai Simons. Christer worked on establishing sensitive and automated shotgun lipidomics technology to would enable fundamental cell biological studies into the principles of lipid sorting in the secretory pathway, receptor activation as well as viral budding from infected cells. This work led to the first comprehensive and quantitative lipidome of a eukaryotic cell and its subcellular organelles. The established lipidomics technology was further developed and is today in wide-spread use in academic as well as commercial settings for clinical lipidomics.

Starting his independent work as an Associate Professor at the University of Southern Denmark, Christer switched his focus to system biology studies of the regulation of lipid metabolic networks. The Ejsing lab has developed multi-omics technology and computational workflows for lipid metabolic flux analysis, data integration and dynamic data visualization. The lab uses this technology for functional studies of how entire lipid metabolic networks are regulated at systems-level in cells and at the whole-body level in animals.

In 2016, Christer was awarded the prestigious Walter A. Shaw Young Investigator Award in Lipid Research by the American Society for Biochemistry and Molecular Biology for his outstanding research contributions in the area of lipids.